Our Pipeline

Pipeline icon

Leading the Way in Cell Therapy

Our pipeline of cancer therapies in the areas of cell therapy, immuno-oncology, and targeted therapies includes investigational therapies and next-generation technologies that have the power to transform the way cancer is treated. As we look to the future, we remain focused on advancing technologies that could someday address additional hematological malignancies and solid tumors.

PROGRAM

PHASE

PHASE 1
PHASE 2
PHASE 3
NDA / BLA / MAA

Axi-cel

PHASE 3

Trial:

ZUMA-7

2L DLBCL

CLINICAL TRIALS

Axi-cel

PHASE 2

Trial:

ZUMA-5

Indolent NHL

CLINICAL TRIALS

Axi-cel

PHASE 2

Trial:

ZUMA-14

3L DLBCL (+rituximab)

CLINICAL TRIALS

Axi-cel

PHASE 2

Trial:

ZUMA-12

1L HR DLBCL

CLINICAL TRIALS

Axi-cel

PHASE 2

Trial:

N/A

3L DLBCL (+mavrilimumab)

Axi-cel

PHASE 1

Trial:

ZUMA-11

DLBCL (+utomilumab)

CLINICAL TRIALS

Axi-cel

PHASE 1

Trial:

ZUMA-19

3L DLBCL (+lenzilumab)

CLINICAL TRIALS

Brexu-cel

PHASE 2

Trial:

ZUMA-3

Adult ALL

CLINICAL TRIALS

Brexu-cel

PHASE 2

Trial:

ZUMA-4

Pediatric ALL

CLINICAL TRIALS

Brexu-cel

PHASE 1

Trial:

ZUMA-8

CLL

CLINICAL TRIALS

KITE-718 (MAGE A3/A6)

PHASE 1

Trial:

N/A

Solid Tumor

CLINICAL TRIALS

KITE-439 (HPV16 E7)

PHASE 1

Trial:

N/A

Solid Tumor

CLINICAL TRIALS

Axi-cel: Axicabtagene Ciloleucel.
Brexu-cel: Brexucabtagene Autoleucel, formerly KTE-X19.
ALL: Acute lymphocytic leukemia.
CLL: Chronic lymphocytic leukemia.
DLBCL: Diffuse large B-cell lymphoma.
iNHL: Indolent non-Hodgkin lymphoma.
MCL: Mantle cell lymphoma.

The safety and efficacy of these investigational agents or investigational uses of marketed products have not been established. These uses have not been approved by the US Food and Drug Administration or other regulatory authorities. There is no guarantee that these therapies or uses will be commercialized.

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